Cheque Drops (Mibolerone)


Cheque Drops (Mibolerone)

Known to many but used by a few, what is it about this oral 19-nor derivative that gave it so much hype back in the day?

First developed in 1963 strictly for veterinary purposes, Cheque Drops were used to disrupt the normal menstrual cycle in female dogs to prevent them from going into heat. However, it is not used commonly anymore due to the side effects noticed in the dogs, such as clitoral enlargement, liver damage and aggression. After the early 2000s this drug was discontinued.

Cheque drops were derived from nandrolone (Deca). They are structurally similar apart from the addition of a methyl carbon group at the 17-alpha carbon, to make it orally bioavailable, and a methyl group at carbon 7 which inhibits 5-alpha reduction and increases androgenicity. It is very resistant to metabolism and to being bound to a protein (which would render it inactive whilst still in the body). This creates a very potent and biologically active compound. This is also why this drug is found on a microgram, as opposed to a typical milligram, basis. It is different to nandrolone in that it is far more androgenic and oestrogenic. In addition, it is highly progestogenic. This makes it a potent bulking agent and pre-contest aggression stimulant.


What are the side effects?
Oestrogenic side effects are very common due to the conversion of this compound to a highly active form of oestrogen. This means the risk of gynecomastia and water retention are very high. It is therefore advised to use an anti-oestrogen whilst using this drug.

As mentioned above, Cheque Drops are also progestogenic. This will augment the effects of oestrogen on tissues in the body and may also cause gynecomastia even with the use of anti-oestrogens.

Cheque Drops are far more androgenic than Nandrolone meaning that typical androgen related side effects can be expected whilst using this compound, such as balding, virilization, acne, etc.

Cheque drops are toxic to the liver and therefore liver supplements should be used whilst using them.

Testosterone suppression can also be expected whilst using this drug.

As with most steroids and since it is resistant to breakdown by the liver, deleterious changes to one’s cholesterol can be expected. Aerobic exercise and good dietary habits are required to prevent such effects.

How is it used?
This drug is typically used for a period of 4 to 8 weeks. The half-life is between 2 to 4 hours and therefore multiple dosages are required per day if stable serum levels are wanted. Some advised that it only be taken pre-workout to give extra aggression in the gym as well as strength. This drug is not typically used in an endurance setting due to the water retention which would not benefit endurance sports. 200 to 500 micrograms are used daily.

This is everything you need to know about Cheque Drops.


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