Everything you need to know about Anadrol.
Multiple people claim that Anadrol (Also known as oxymetholone, Anapolon or Anaps) is one of the strongest oral anabolic steroids on the black market. It is said to be a mixture of Dianabol and Superdrol giving the individual both strength and muscle size. Let us see what the science behind this notorious drug states.
First described in 1959, Anadrol became available on the drug market for treatment of muscle wasting conditions and osteoporosis. However, shortly after its release, the FDA regulated its use and made sure it was only prescribed for anaemia caused by poor blood cell production since it potently stimulated red blood cell production. Production was increased by 5 times baseline. It was not long until Anadrol was replaced by recombinant erythropoietin for this purpose. This led to Anadrol being investigated for its use in HIV/AIDS related muscle wasting and it was shown to be very effective in this regard. Pharmaceutical grade Anadrol is difficult to come across since it has very few uses.
Anadrol is a derivative of DHT (dihydrotestosterone – which produced through reduction of testosterone). This drug appears to be highly oestrogenic meaning it converts to oestrogen. This does not make sense since it is a DHT derivative and DHT does not convert to oestrogen. Thus, it is postulated that oestrogen is not actually the problem and that it is the conversion of Anadrol to progestins (which act similarly to oestrogen) that causes the side effects. Subsequent studies failed to prove this and thus a new hypothesis is that Anadrol stimulates oestrogen receptors. This is the reason there is a lot of water weight that can be expected when using this compound. The water weight does have benefits, however. The muscle will be fuller, and this will aid in better contraction. In addition, the water weight will provide joint and tendon protection by more being stored around the connective tissues.
What are the side effects?
As mentioned above, oestrogen side effects will be a problem. Typical aromatase inhibitors do not appear to work since Anadrol does not aromatise and thus, Tamoxifen (Nolvadex) which influences the oestrogen receptor sensitivity should be utilised instead to prevent oestrogen side effects.
At higher doses, androgenic side effects will be experienced. This includes, acne, oily skin, hair loss, virilisation of women, etc. At low doses, Anadrol is surprisingly safe in women and does not cause these unwanted side effects.
Anadrol is c17-alpha alkylated and thus will be metabolised by the liver and toxic to the liver. Limiting the duration of use to 4 to 6 weeks can reduce the incidence of liver dysfunction. At doses between 50 to 100mg, studies showed there to be significant elevations in liver enzymes in the 100mg group, indicating liver toxicity.
Anadrol, like other anabolic steroids, will increase bad cholesterol (LDL) and decrease good cholesterol (HDL). In the study mentioned above, LDL change was not significant, however, HDL was reduced drastically. Therefore, a healthy diet should be instituted along with cardiovascular exercise.
Blood pressure increases have been shown to occur with Anadrol. This is due to water retention and decreased blood vessel reactivity. Therefore, it is important to control blood pressure when using this drug, either by lifestyle changes or the addition of anti-hypertensive agents.
It is also important to remember that testosterone suppression will occur and thus a post-cycle therapy will be required to re-establish natural testosterone production.
How is it used?
For treatment of anaemia, a dose of 1 to 2 mg per kilogram of bodyweight is used. For athletic performance, a dose of 25 to 150 mg a day is taken for 4 to 8 weeks.
This is everything you need to know about Anadrol.